Okay, so I just got a neato tablet and I want to use it for certain things in my comic (in fact, I'm about to wipe my comic and start new), and I'd probably want to do some completely ON the tablet. This means, I won't use paper and I won't scan it, automatically being in 300 DPI--which raises the question, if I eventually wanted to print it, how big of a file should I start messing with the tablet on? Took a little 8 1/2 x 11 scan and chopped it up, have about 2,500 x 3,300, so that's what I'm working with for now. What do you folks use?
(Also, anybody got any freebie neato tablet tips for me?

)
Oh, also, that's the general format I'd use for my comic--kind of like an actual comic book, 8 1/2 x 11 or whatever.